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Monday, December 5, 2011
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Sunday, December 4, 2011
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Saturday, December 3, 2011
2011 ASH Annual Meeting to highlight latest hematology research, clinical care breakthroughs
[ | E-mail |
Contact: Lindsey Love
llove@hematology.org
202-552-4925
American Society of Hematology
WASHINGTON The American Society of Hematology (ASH) will host more than 20,000 attendees from around the globe at its 53rd annual meeting December 10-13 at the San Diego Convention Center in San Diego, CA. The ASH annual meeting, the premier medical meeting for physicians and researchers in the field, will showcase the latest research and clinical advances in hematology.
"2011 has proven to be an inspiring and rewarding year for hematology, filled with new discoveries that are bringing us one step closer to conquering blood diseases," said ASH President J. Evan Sadler, MD, PhD, of the Washington University School of Medicine in St. Louis. "I hope that these scientific presentations, coupled with the diverse offering of educational and professional development opportunities at the Society's 53rd Annual Meeting, will leave attendees inspired to use their new knowledge to further advance the field in 2012."
Data from more than 4,200 scientific abstracts representing more than 1,000 oral and 3,000 poster presentations will reveal the latest research in the field during the meeting. These include six of the top-scoring abstracts to be highlighted during the Plenary Scientific Session and six Late-Breaking Abstracts representing studies with novel data of high impact.
Exciting new offerings for the 2011 ASH Annual Meeting include a Special Symposium on quality of care, "Quality Indicators: Examples and Relevance to Hematology," which will focus on clinical areas of hematology for which quality indicators have been developed and are available. This new symposium will examine how such quality measures are derived and measured, and the importance of adhering to these standards.
The 2011 meeting also marks the debut of the ASH annual meeting mobile application for iPhone, Android, and Blackberry smartphones, as well as iPad and Android tablet devices. This exclusive app, available now in iTunes and the Android Market, and coming soon to Blackberry AppWorld, will feature full text of all annual meeting abstracts, articles from Hematology 2011 (The Education Program Book), maps, exhibitor listings, and other general meeting information.
Other 2011 ASH Annual Meeting highlights include special symposia, the Education Program, the Scientific Program, and a host of lectures and seminars. The Education Program will offer nearly 30 sessions on important areas of clinical progress, including advances in genomic studies of hematologic malignancies and new management strategies for bone failure syndromes, as well as two sessions held jointly with the American Association of Blood Banks (AABB) on transfusion medicine. The Scientific Program will feature 17 sessions on the hottest areas of hematology research, including discussions of metabolic and DNA methylation changes in leukemia and innovative strategies to enhance regenerative potential of hematopoietic stem cells.
Several renowned hematologists will present this year's Special Lectures. Peter Carmeliet, MD, PhD, will examine the fundamentals and medical relevance of angiogenesis during the 2011 Ham-Wasserman Lecture, "Angiogenesis in Health and Disease," on Saturday, December 10. On Monday, December 12, George Q. Daley, MD, PhD, will present the E. Donnall Thomas Lecture, "Hematopoietic, Embryonic, and Induced Pluripotent Stem Cells: Diseases, Myths, and Medicines," which will explore the possibilities and obstacles surrounding the use of genetically modified human embryonic stem cells and personalized induced pluripotent cells derived from patients by somatic cell reprogramming. Also on Monday, December 12, Ernest Beutler Lecture and Prize recipients Janet D. Rowley, MD, and Brian J. Druker, MD, will highlight their achievements in chronic myeloid leukemia research and treatment during their lecture, "Chronic Myeloid Leukemia (CML): A Success Story from Chromosomes to Effective Therapy." The Presidential Symposium on Tuesday, December 13, will focus on recent advances in understanding bone marrow failure syndromes, featuring Monica Bessler, MD, PhD, Benjamin Ebert, MD, DPhil, and Alan D'Andrea, MD.
The Society will honor several hematologists with individual awards for their achievements during the 2011 meeting. On Sunday, December 11, ASH will honor David Nathan, MD, with the Society's highest award, the Wallace H. Coulter Award for Lifetime Achievement in Hematology, for his important discoveries in thalassemia and other blood disorders, his tireless promotion of translational research, and his dedication to training several generations of leaders in the field. ASH will also recognize Nancy C. Andrews, MD, PhD, and Malcolm K. Brenner, MD, PhD, with Mentor Awards on Sunday for their sustained commitment to the training and career development of junior hematologists. On Tuesday, December 13, ASH will present Christoph Klein, MD, PhD, with the Dameshek Prize for his outstanding accomplishments, which have had a large impact on the understanding of human blood and the immune system. Also on Tuesday, Ching-Hon Pui, MD, will receive the Henry M. Stratton Medal for his many significant contributions to childhood leukemia research.
###
For the complete annual meeting program and abstracts, visit http://www.hematology.org/2011abstracts. Up-to-the-minute meeting information can also be found at ASH's Twitter feed, or by following the annual meeting conversation at #ASH11. The American Society of Hematology is the world's largest professional society concerned with the causes and treatment of blood disorders. Its mission is to further the understanding, diagnosis, treatment, and prevention of disorders affecting blood, bone marrow, and the immunologic, hemostatic, and vascular systems by promoting research, clinical care, education, training, and advocacy in hematology. The official journal of ASH is Blood, the most cited peer-reviewed publication in the field, which is available weekly in print and online.
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
[ | E-mail |
Contact: Lindsey Love
llove@hematology.org
202-552-4925
American Society of Hematology
WASHINGTON The American Society of Hematology (ASH) will host more than 20,000 attendees from around the globe at its 53rd annual meeting December 10-13 at the San Diego Convention Center in San Diego, CA. The ASH annual meeting, the premier medical meeting for physicians and researchers in the field, will showcase the latest research and clinical advances in hematology.
"2011 has proven to be an inspiring and rewarding year for hematology, filled with new discoveries that are bringing us one step closer to conquering blood diseases," said ASH President J. Evan Sadler, MD, PhD, of the Washington University School of Medicine in St. Louis. "I hope that these scientific presentations, coupled with the diverse offering of educational and professional development opportunities at the Society's 53rd Annual Meeting, will leave attendees inspired to use their new knowledge to further advance the field in 2012."
Data from more than 4,200 scientific abstracts representing more than 1,000 oral and 3,000 poster presentations will reveal the latest research in the field during the meeting. These include six of the top-scoring abstracts to be highlighted during the Plenary Scientific Session and six Late-Breaking Abstracts representing studies with novel data of high impact.
Exciting new offerings for the 2011 ASH Annual Meeting include a Special Symposium on quality of care, "Quality Indicators: Examples and Relevance to Hematology," which will focus on clinical areas of hematology for which quality indicators have been developed and are available. This new symposium will examine how such quality measures are derived and measured, and the importance of adhering to these standards.
The 2011 meeting also marks the debut of the ASH annual meeting mobile application for iPhone, Android, and Blackberry smartphones, as well as iPad and Android tablet devices. This exclusive app, available now in iTunes and the Android Market, and coming soon to Blackberry AppWorld, will feature full text of all annual meeting abstracts, articles from Hematology 2011 (The Education Program Book), maps, exhibitor listings, and other general meeting information.
Other 2011 ASH Annual Meeting highlights include special symposia, the Education Program, the Scientific Program, and a host of lectures and seminars. The Education Program will offer nearly 30 sessions on important areas of clinical progress, including advances in genomic studies of hematologic malignancies and new management strategies for bone failure syndromes, as well as two sessions held jointly with the American Association of Blood Banks (AABB) on transfusion medicine. The Scientific Program will feature 17 sessions on the hottest areas of hematology research, including discussions of metabolic and DNA methylation changes in leukemia and innovative strategies to enhance regenerative potential of hematopoietic stem cells.
Several renowned hematologists will present this year's Special Lectures. Peter Carmeliet, MD, PhD, will examine the fundamentals and medical relevance of angiogenesis during the 2011 Ham-Wasserman Lecture, "Angiogenesis in Health and Disease," on Saturday, December 10. On Monday, December 12, George Q. Daley, MD, PhD, will present the E. Donnall Thomas Lecture, "Hematopoietic, Embryonic, and Induced Pluripotent Stem Cells: Diseases, Myths, and Medicines," which will explore the possibilities and obstacles surrounding the use of genetically modified human embryonic stem cells and personalized induced pluripotent cells derived from patients by somatic cell reprogramming. Also on Monday, December 12, Ernest Beutler Lecture and Prize recipients Janet D. Rowley, MD, and Brian J. Druker, MD, will highlight their achievements in chronic myeloid leukemia research and treatment during their lecture, "Chronic Myeloid Leukemia (CML): A Success Story from Chromosomes to Effective Therapy." The Presidential Symposium on Tuesday, December 13, will focus on recent advances in understanding bone marrow failure syndromes, featuring Monica Bessler, MD, PhD, Benjamin Ebert, MD, DPhil, and Alan D'Andrea, MD.
The Society will honor several hematologists with individual awards for their achievements during the 2011 meeting. On Sunday, December 11, ASH will honor David Nathan, MD, with the Society's highest award, the Wallace H. Coulter Award for Lifetime Achievement in Hematology, for his important discoveries in thalassemia and other blood disorders, his tireless promotion of translational research, and his dedication to training several generations of leaders in the field. ASH will also recognize Nancy C. Andrews, MD, PhD, and Malcolm K. Brenner, MD, PhD, with Mentor Awards on Sunday for their sustained commitment to the training and career development of junior hematologists. On Tuesday, December 13, ASH will present Christoph Klein, MD, PhD, with the Dameshek Prize for his outstanding accomplishments, which have had a large impact on the understanding of human blood and the immune system. Also on Tuesday, Ching-Hon Pui, MD, will receive the Henry M. Stratton Medal for his many significant contributions to childhood leukemia research.
###
For the complete annual meeting program and abstracts, visit http://www.hematology.org/2011abstracts. Up-to-the-minute meeting information can also be found at ASH's Twitter feed, or by following the annual meeting conversation at #ASH11. The American Society of Hematology is the world's largest professional society concerned with the causes and treatment of blood disorders. Its mission is to further the understanding, diagnosis, treatment, and prevention of disorders affecting blood, bone marrow, and the immunologic, hemostatic, and vascular systems by promoting research, clinical care, education, training, and advocacy in hematology. The official journal of ASH is Blood, the most cited peer-reviewed publication in the field, which is available weekly in print and online.
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2011-12/asoh-2aa120111.php
End of the line for Cain? Announcement Saturday (AP)
ATLANTA ? Rapidly becoming a mere footnote in the presidential race, Herman Cain sent mixed signals Friday on whether he would abandon his beleaguered White House bid on Saturday after a woman's allegation of an extramarital affair.
He said he would make a "major announcement" on whether he would press on ? at an event still being billed as the grand opening of a new headquarters.
It is the latest ? and perhaps final ? twist in a campaign saga that has taken the Georgia businessman from unknown longshot to surprise frontrunner to embattled tabloid subject.
He arrived at his suburban Atlanta home on Friday afternoon to talk with his wife of 42 years, Gloria, about whether to press on after his campaign was rocked by multiple sexual harassment allegations and this week's claim that he had a 13-year affair. He denies wrongdoing. It was their first face-to-face meeting since the allegation was made public.
As night fell, campaign aides who were optimistic earlier Friday that Cain would press on said privately they expected that he would exit the race.
Earlier, in a speech in Rock Hill, S.C., Cain wouldn't disclose whether he would drop out but told supporters to stay tuned. He said he would clarify the next steps of the campaign and assured backers the affair claim was "garbage." But he also said he needed to consider what he would do with campaign donations already banked if he dropped out of the race.
"Nobody's going to make me make that prematurely," Cain told a crowd of about 100 people. "That's all there is to it."
"My wife and family comes first. I've got to take that into consideration," Cain added. "I don't doubt the support that I have. Just look at the people who are here."
Cain had not seen his wife since Ginger White, 46, came forward and said she had a sexual affair with Cain that lasted more than a decade. He has said they were only friends but acknowledged that he helped pay her monthly bills and expenses. His wife, Cain said, did not know of the friendship with White.
The former Godfather's pizza executive said he is reassessing whether his presidential bid is still viable.
But it was difficult to imagine a path forward with just a month until the lead-off Iowa caucuses.
Polls suggest his popularity has taken a deep hit.
A Des Moines Register poll released Friday showed Cain's support plummeting, with backing from 8 percent of Republican caucusgoers in Iowa, down from 23 percent a month ago.
Fundraising has also fallen off. He issued an email appeal to supporters on Friday asking for donations, in an attempt to gauge whether his financial support has dried up.
"I need to know that you are behind me 100 percent," Cain told backers. "In today's political environment, the only way we can gauge true support is by the willingness of our supporters to invest in this effort.
A political novice, Cain leveraged strong tea party support to hurtle to the front of the Republican pack in October casting himself as an anti-establishment outsider. His catchy 9-9-9 tax overhaul proposal helped his rise. But his effort soon lost altitude.
He fumbled policy questions, and his campaign has been reeling since it was revealed a little more than a month ago that the National Restaurant Association paid settlements to two women who claimed Cain sexually harassed them while he was president of the organization. A third woman told The Associated Press that Cain made inappropriate sexual advances but that she didn't file a complaint. A fourth woman also stepped forward to accuse Cain of groping her in a car in 1997.
Cain has denied wrongdoing in all cases. And his campaign was taking some steps to blunt the drumbeat of allegations.
It unveiled a "Women for Herman Cain" webpage with testimonials from female backers, some urging him to stay in the race. It was led by Gloria Cain.
The candidate's wife ? who's not been on the campaign trail ? has drawn her own support as the allegations against her husband have piled up.
A Facebook page "I Stand With Gloria Cain" had attracted more than 400 supporters by Friday afternoon.
On Friday, Cain urged backers in South Carolina to look past the allegations.
"There's a lot of garbage on the Internet. There's a lot of garbage out there on the TV. There's a lot of garbage out there about me, don't you know? There's a lot of misinformation out there. You have to stay informed and check out the facts for yourself," Cain said.
He added: "I'm on this journey for a reason. I don't look back."
Word of a pending announcement took some aides by surprise.
"I am learning this as you're learning it," said Cain's Iowa campaign chairman, Steve Grubbs, who met Thursday with campaign manager Mark Block.
The two outlined a December travel schedule for Cain, who began advertising on television again in Iowa on Friday.
As of Friday afternoon, Cain was scheduled to participate in the two Iowa debates this month, hold a media announcement in Iowa on Dec. 12 and tour the state at the end of the month.
"That's sort of the plan, very tentatively," Grubbs said. "All that could change."
Georgia supporters set to attend the Saturday event in Atlanta ? billed as a headquarters celebration ? were taken aback by the news that an announcement was coming.
"I have heard nothing," said state Sen. Josh McKoon, a prominent Cain backer who will stand with him Saturday.
___
Philip Elliott reported from Rock Hill, S.C. Associated Press writers Ray Henry in Atlanta, Thomas Beaumont in Iowa and Steve Peoples in New Hampshire contributed to this report.
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Friday, December 2, 2011
Instapundit ? Blog Archive ? AT AMAZON, markdowns in Automotive ...
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Source: http://pjmedia.com/instapundit/132589/
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Court: Some bone marrow donors can be paid (AP)
SAN FRANCISCO ? A federal appeals court ruled Thursday that most bone marrow donors can be paid, overturning the government's interpretation of a decades-old law making such compensation a crime punishable by up to five years in prison.
In its ruling, the 9th U.S. Circuit Court of Appeals said a technological breakthrough makes donating bone marrow a process nearly identical to giving blood plasma.
It's legal ? and common ? to pay plasma donors. Therefore, the court ruled, bone marrow donors undergoing the new procedure can be paid as well and are exempt from a law making it a felony to sell human organs for transplants.
The unanimous, three-judge panel of the court did say it remains a felony to compensate donors for undergoing an older transplant method, which extracts the marrow from the donors' bones.
But the court said the new technology isn't covered by the law because actual bone marrow isn't taken from the donor. Instead, specialized cells that grow into marrow are taken from a donor's bloodstream, and it's basically a blood donation, not an organ transplant, the court said. It noted that two-thirds of bone marrow transplants employ the newer process.
Tens of thousands of people with leukemia, lymphoma and other blood diseases are saved each year by such procedures. An estimated three thousand others die waiting for donations, which unlike simple blood donations need to be genetically compatible, making matches especially difficult for African Americans.
Advocates for paying donors said compensation will spur even more donations. Detractors argue that donor compensation will exploit the poor to undergo risky medical procedures to benefit the wealthy.
The National Marrow Donor Program, the nonprofit that provides transplants from volunteers, opposes payments.
"We were surprised and puzzled by the appellate court's decision regarding allowing compensation," said Michael Boo, the program's chief strategy officer. "The National Marrow Donor Program is studying the decision and assessing the impact. We do not anticipate the ruling will change the NMDP's current policies and practices."
The ruling overturns a lower court decision barring compensation for all bone marrow donations.
The lawsuit was filed by lawyers at the nonprofit Institute for Justice, representing a coalition of patients, doctors and MoreMarrowDonors.org, which is seeking to offer donors $3,000 in the form of a scholarship, housing allowance or gift to charity.
A plaintiff in the lawsuit, Kumud Majumder, said his 11-year-old son, Arya, died of leukemia last April.
The family had resorted to an imperfect bone marrow donor match in desperation because no perfect match was available, the father said at a news conference outside the circuit court's Pasadena chambers
"Arya's tragedy happened in part because of a lack of bone marrow donors," Majumder said. "In the end, creating more and better bone marrow donor matches through a system of modest compensation will save the lives of patients, improve the lives of donors, drive down the costs of treatment and improve the quality of life of cancer patients as they battle to survive."
At the heart of the court's ruling, which is sure to ignite renewed debate over paying medical donors, are two processes for transplanting bone marrow into patients suffering from diseases of the blood.
The first and older one is known as "aspiration" and requires the donor to endure painful and risky procedures that require hospitalization and anesthesia. Long, thick needles are inserted into the cavities of the donor's hip bones to suck out the bone marrow. The court said that process was still covered by the National Organ Transplant Act, which explicitly prohibits paying donors for their bone marrow.
"The point of the ban on selling organs is to protect people from ignoring the medical risk for money," said Arthur Caplan, a bioethicist with the University of Pennsylvania. Caplan said the ruling Thursday may unintentionally support campaigns to pay donors in other medical fields such as compensating women for their eggs.
The newer procedure, which the court ruled exempt from the act, was developed about 20 years ago and involves harvesting cells from the bloodstream rather than in bone. Called "apheresis," the procedure requires the donor to undergo five days of drug injections to stimulate production of specialized blood cells. Then the donor sits in a recliner for several hours while the blood is filtered through a machine that extracts the specialized cells.
"Congress could not have had an intent to address the apheresis method when it passed the statute, because the method did not exist at that time," Judge Andrew Kleinfeld wrote for the court. "We construe `bone marrow' to mean the soft, fatty substance in bone cavities, as opposed to blood, which means the red liquid that flows through the blood vessels."
Kleinfeld said it may be time to apply a new label to the process.
"It may be that `bone marrow transplant' is an anachronism that will soon fade away, as peripheral blood stem cell apheresis replaces aspiration as the transplant technique, much as `dial the phone' is fading away now that telephones do not have dials," Kleinfeld wrote.
The decision won't become official for at least 30 days while the U.S. Department of Justice ponders what to do next. The DOJ can ask the appeals court to reconsider the decision or petition the U.S. Supreme Court to take it.
DOJ spokesman Charles Miller said the department is reviewing its options.
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